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KMID : 0615720030200010035
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Jouranl of Korean Acupuncture and Moxibustion society
2003 Volume.20 No. 1 p.35 ~ p.50
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Effect of Bee Venom Therapy in a Rat Femoral Artery Model induced Vasospasm
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Abstract
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In order to study the effect of Bee venom(BV) on the subarachnoid hemorrhage animal model, the autologous whole blood was applied to the vicinity of the sprague dawley rat right femoral artery. Following periarterial application of autologous whole blood(PAB) and intraperitoneal injection of BV(1:5,000 nd !:500), the vasomotor responses to BV(from 1:500,000 to 1:500) were identified and the histological changes, neovascularized blood vessel were observed.
We have shown that alterations in vasomotor and histological findings are elicited following application of periarterial blood and i.p. injection of BV(1:5,000 and 1:500) induced heavy vasospasm and eovascularization on the subarachnoid hemorrhage like model form peripheral artery.
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